and efficacy of such
herbs and the ultimate formulations.
mere collection of herbs does not constitute an Ayurvedic remedy.
An herbal product containing the same degree of safety and
efficacy, as an Ayurvedic product may not deliver the same degree
of safety and efficacy, as ayurveda prescribes specific processing
that enhances both efficacy and safety. This summarizes the
essential differences between herbal & Ayurvedic medicine. The
particular composition and complicated processing characteristics
of an Ayurvedic remedy aim at achieving comprehensive treatment
with no-side effects.
The principle of treatment for various diseases and ailment has
been precisely laid out in Ayurvedic text. They involve
formulation of various herbs and minerals in precise proportions
with specific processing methods. A careful choice of the right
plant by trained personnel is followed by prudent selection of the
parts to be processed, i.e. the leaves, seeds, stem, bark or
roots. Each step is vital and many cause unsatisfactory
pharmacological results when not executed with utmost care.
Realizing the rapid changes in the environment, and that all our
ingredients are procured from plants exposed to these
environmental conditions, quality control process, by necessity,
have to be very stringent. In essence, once the medicinal herb
step into the lab from nature’s lap, it traverses a highly
scientific path: Pharmacognosy, where is authenticity is
established by morphological and microscopic means; analytical
chemistry, where physical and chemical parameters are analyzed and
studied; animal pharmacology, where elaborate experimental studies
such as acute, sub-chronic, chronic toxicity, teratogenicity,
mutagenicity and carcinogenicity studies are conducted, not only
to assess the efficacy, but also to ensure the safety, after which
it is further tested for immunological, histopathological and
biochemical parameters. The Formulation and Development Division,
where the final formulations made, conducts accelerated stability
trials and estimates shelf-life. The final product is further
standardized using state of art techniques such as High
performance Liquid Chromatography (HPLC), Gas Liquid
Chromatography (GLC), High Performance Thin Layer Chromatography (HPTLC
Finger printing), Atomic Absorption Spectrophotometry (ASS), etc.,
which ensure physical and chemical uniformity and rule out the
presence of impurities, aflatoxins, pesticides and heavy metals.
Once these basic parameters are fulfilled, the product undergoes
Phase I, II and III clinical studies to establish its safety,
tolerability and efficacy. The journey of the finished product
then continues to microbiology, where the microbial counts, if
any, are monitored and the stability is tested.
The Zoetic Ayurvedics with its several years of expertise,
thus transforms the crude herb into a valuable constituent of a
high quality product. Truly, a fascinating story of the travails
of a herb to a formulation.